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Related Experiment Videos

Strain variation in 59Fe absorption during aflatoxicosis

G M Lanza, K W Washburn, R D Wyatt

    Poultry Science
    |March 1, 1981
    PubMed
    Summary

    Dietary aflatoxin negatively impacts broiler chickens, reducing iron absorption and causing anemia in commercial strains. This study highlights strain-specific responses to aflatoxicosis in poultry.

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    Area of Science:

    • Poultry Science
    • Toxicology
    • Animal Nutrition

    Background:

    • Aflatoxins are toxic secondary metabolites produced by fungi that contaminate animal feed.
    • Poultry are susceptible to aflatoxicosis, which can cause various health issues, including impaired nutrient absorption.
    • Iron is an essential mineral for poultry health, and its absorption can be affected by mycotoxins.

    Purpose of the Study:

    • To investigate the impact of dietary aflatoxin on iron absorption in different broiler chicken strains.
    • To determine if there is strain-specific variation in the response to aflatoxin exposure regarding iron metabolism.
    • To assess the relationship between aflatoxin-induced anemia and iron absorption in broilers.

    Main Methods:

    • Three strains of broiler chickens (two commercial, one randombred) were fed diets containing aflatoxin.
    • Body weights, mortality, and hematocrit levels were monitored.
    • Iron absorption was measured in the different experimental groups.

    Main Results:

    • Aflatoxin exposure led to reduced body weight and increased mortality across all tested strains.
    • Commercial broiler strains exhibited significantly reduced hematocrit levels (anemia) when fed aflatoxin, unlike the randombred strain.
    • Dietary aflatoxin impaired iron absorption in all strains, irrespective of whether anemia was present.

    Conclusions:

    • Dietary aflatoxin poses a significant health risk to broiler chickens, affecting growth, survival, and iron metabolism.
    • Commercial broiler strains appear more susceptible to aflatoxin-induced anemia than randombred strains.
    • Aflatoxin reduces iron absorption in poultry, a finding consistent across different genetic backgrounds and anemia status.

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