[Enzyme changes in the myocardium of experimental animals exposed to noise of various intensities]

The activity of the enzymes: SDH,GIDH,LDH, GI-6-PDH, ATP-ase,PGM, G 6P-ase, PI, 6P-ase in myocardial tissue were studied under conditions of a 30-day experiment on albino rats, treated two hours daily, 5 days in the week, with noise with an intensity of 85 dB/A/ and 95 dB/A/. Under the effect of noise with intensity of 85 dB/A/ a tendency to inhibition of SDH and GIDH activity is observed, which after the treatment with 95 dB/A/ noise is statistically significant. With the latter noise level a significant enhancement of PI,6 P-ase activity is established as well as a tendency to enhancement of G6P-ase and ATP-ase activity. The data from the investigations carried out reveal the possibility of developing disturbances in the metabolism of myocardial tissue under noise effect.