[Extrusion of nucleolus-like bodies from the nuclei of human oocytes]

A morphological and cytochemical analysis of nucleolus-like bodies extruded in antenatal human development phase from the nucleus into the oocyte cytoplasm has been carried out, and the quantitative dynamics of this phenomenon is evaluated. The nucleolus-like bodies are Feulgen-negative, pyroninophilic, and measuring 4-5 micron in diameter. These bodies migrate from the nuclei of oogonia and oocytes at all the meiotic prophase 1 stages, from the preleptotene chromosome condensation stage on. The frequency of extrusion of nucleolus-like bodies at the diplotene stage is lower than that at the dictyatene stage.