[Hemolysis and plasma proteins (author's transl)]

Simultaneous assay of haptoglobulin, hemopexin and orosomucoid allowed detection and quantification of intravascular hemolysis with or without inflammatory reactions. In cases of intravascular or extravascular hemolysis, the concentration of plasma haptoglobulin is greatly diminished, this generally being accompanied by an increase in free bilirubin. This last characteristic allows differentiation from intravascular hemolysis where the free bilirubin concentration remain normal.