Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Bronchial mucociliary function. A new diagnostic technic]

T Todisco, V Grassi, R Palumbo

    Bollettino Della Societa Italiana Di Biologia Sperimentale
    |August 15, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Second-line therapies after CDK4/6 inhibitor failure in HR-positive/HER2-negative metastatic breast cancer patients: real-world data from the HERMIONE-13 study.

    ESMO real world data and digital oncology·2026
    Same author

    Attending an integrated nephrology and diabetology outpatient service can improve diabetic kidney disease treatment: a single-center experience.

    Acta diabetologica·2025
    Same author

    The role of individual differences in environmental sensitivity in teachers' stress and burnout at work.

    Stress and health : journal of the International Society for the Investigation of Stress·2024
    Same author

    Surgeon eye lens dose monitoring in interventional neuroradiology, cardiovascular and radiology procedures.

    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2022
    Same author

    Efficacy of short-term induction therapy with low-dose testosterone as a diagnostic tool in the workup of delayed growth and puberty in boys.

    Journal of endocrinological investigation·2022
    Same author

    Learned self-regulation in top-level managers through neurobiofeedback training improves decision making under stress.

    Scientific reports·2022
    Same journal

    Interaction between electromagnetic waves and auditory organs.

    Bollettino della Societa italiana di biologia sperimentale·2002
    Same journal

    Epibiotic bacteria in the marine ecosystem.

    Bollettino della Societa italiana di biologia sperimentale·2002
    Same journal

    Influence of static magnetic fields on cell viability, necrosis and apoptosis.

    Bollettino della Societa italiana di biologia sperimentale·2002
    Same journal

    Knowledge of brain memory codification as a challenge for the third millennium.

    Bollettino della Societa italiana di biologia sperimentale·2002
    Same journal

    Methyleugenol and eugenol variation in Ocimum basilicum cv. Genovese gigante grown in greenhouse and in vitro.

    Bollettino della Societa italiana di biologia sperimentale·2002
    Same journal

    Prophylaxia of cystine calculosis by alpha-mercaptopropionyl-glycine administered continuously or every other day.

    Bollettino della Societa italiana di biologia sperimentale·2002
    See all related articles

    Low mucociliary clearance (m.c.c.) in non-smokers indicates higher risk for lung diseases. This study used 99mTc-labeled spherocytes to assess m.c.c., finding potential high-risk individuals.

    Area of Science:

    • Pulmonary Medicine
    • Nuclear Medicine
    • Respiratory Physiology

    Background:

    • Mucociliary clearance (m.c.c.) is crucial for airway defense.
    • Assessing central airway m.c.c. is important for diagnosing respiratory conditions.
    • Previous methods for m.c.c. assessment have limitations.

    Purpose of the Study:

    • To evaluate a novel method for assessing central airway mucociliary clearance using 99mTc-labeled autologous spherocytes.
    • To identify individuals with potentially impaired mucociliary clearance.
    • To explore the utility of spherocyte inhalation for visualizing central airways.

    Main Methods:

    • Inhalation of aerosolized 99mTc labeled autologous spherocytes.
    • Measurement of mucociliary clearance rates in normal non-smoking subjects and patients with chronic bronchitis.

    Related Experiment Videos

  • Analysis of central deposition patterns of the inhaled spherocytes.

    • Main Results:

    • Abnormally low mucociliary clearance was observed in 3 out of 8 normal non-smoking subjects.
    • Very low m.c.c. rates were also found in 2 out of 6 non-smoking patients with chronic bronchitis.
    • The inhaled spherocytes showed good central deposition, suggesting potential for airway visualization.

    Conclusions:

    • Non-smoking individuals with low mucociliary clearance may be considered "high-risk subjects" for developing broncho-pulmonary diseases.
    • The 99mTc-labeled spherocyte method is a promising tool for assessing central airway m.c.c.
    • This technique may offer a non-invasive method for visualizing central airways in critically ill patients.