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[Neuropathology and pregnancy. 189 consecutive cases (1971--1976) (author's transl)]

C Faguer, Y Darbois, D Pathier

    Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
    |September 1, 1978
    PubMed
    Summary

    Pregnancy with neurological disorders generally has a good prognosis with appropriate treatment. However, conditions like cerebral vascular accidents significantly worsen outcomes, while stabilized disseminated sclerosis is compatible with normal pregnancy.

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    Area of Science:

    • Neurology
    • Obstetrics
    • Maternal-Fetal Medicine

    Context:

    • Reviews 189 case histories of pregnant women with pre-existing or newly diagnosed neurological disorders.
    • Focuses on the interplay between pregnancy and various neuropathologies.
    • Highlights the importance of the timing of neurological condition diagnosis during pregnancy.

    Purpose:

    • To analyze the prognosis and compatibility of pregnancy with diverse neurological conditions.
    • To identify factors influencing pregnancy outcomes in women with neuropathology.
    • To assess the impact of specific neurological disorders, such as vascular accidents and tumors, on pregnancy.

    Summary:

    • Most neurological conditions (epilepsy, psychoses, tumors, disseminated sclerosis) are compatible with normal pregnancy if managed appropriately.

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  • Cerebral vascular accidents present a poor prognosis, with neurosurgery offering potential hope.
  • Pituitary adenomas are increasingly frequent among cerebral tumors in pregnancy.
  • Stabilized disseminated sclerosis allows for normal pregnancy outcomes.
  • Psychopathies pose complex challenges during pregnancy.
  • Impact:

    • Provides crucial insights for managing pregnant women with neurological conditions.
    • Emphasizes the generally favorable prognosis with continued appropriate medical care.
    • Underscores the critical impact of specific conditions like vascular accidents on maternal and fetal outcomes.