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Related Concept Videos

Plastic Deformations of Members with a Single Plane of Symmetry01:21

Plastic Deformations of Members with a Single Plane of Symmetry

346
When a structural member undergoes plastic deformation due to bending, it is crucial to understand the position of the neutral axis and the stress distribution. This member, characterized by a single plane of symmetry, exhibits a uniform stress distribution, with negative stress above the neutral axis and positive stress below. Notably, the neutral axis does not align with the centroid of the cross-section. This misalignment is typical in cases where the cross-section is not rectangular or...
346
Plastic Deformations01:19

Plastic Deformations

436
Plastic deformation represents a fundamental concept in materials science, which explains the irreversible change in the shape of a material when it experiences stress beyond its elastic capability. This phenomenon is important in structural engineering, especially in designing and analyzing cantilever beams—structures that are securely fixed at one end and bear loads at the opposite end. When these beams are subjected to loads within their elastic range, they will return to their...
436
Plastic Deformations01:14

Plastic Deformations

407
It is essential to understand how structural members behave under plastic deformation when the bending stress exceeds the material's yield strength. This state of deformation permanently alters the shape of the member, in contrast to the linear elastic behavior observed before yielding. The strain at any point in the member is expressed in terms of maximum strain. Notably, the neutral axis, which coincides with the centroid during elastic bending, shifts away from the centroid under plastic...
407
Temperature Dependent Deformation01:12

Temperature Dependent Deformation

369
In a nonhomogeneous rod made up of steel and brass, restrained at both ends and subjected to a temperature change, several steps are involved in calculating the stress and compressive load. Due to the problem's static indeterminacy, one end support is disconnected, allowing the rod to experience the temperature change freely. Next, an unknown force is applied at the free end, triggering deformations in the rod's steel and brass portions. These deformations are then calculated and added...
369
Deformations in a Symmetric Member in Bending01:18

Deformations in a Symmetric Member in Bending

480
When analyzing the deformation of a symmetric prismatic member subjected to bending by equal and opposite couples, it becomes clear that as the member bends, the originally straight lines on its wider faces curve into circular arcs, with a constant radius centered at a point known as Point C. This phenomenon helps to understand the stress and strain distribution within the member more clearly.
When the member is segmented into tiny cubic elements, it is observed that the primary stress...
480
Deformation of Member under Multiple Loadings01:11

Deformation of Member under Multiple Loadings

450
When a rod is made of different materials or has various cross-sections, it must be divided into parts that meet the necessary conditions for determining the deformation. These parts are each characterized by their internal force, cross-sectional area, length, and modulus of elasticity. These parameters are then used to compute the deformation of the entire rod.
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
450

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Related Experiment Video

Updated: Jan 21, 2026

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
09:12

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

Published on: January 12, 2018

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Effect of pentoxifylline on single red cell deformability

D Seiffge, H Kiesewetter

    Klinische Wochenschrift
    |November 16, 1981
    PubMed
    Summary

    Pentoxifylline improves red blood cell deformability after calcium-induced stress. This study measured red blood cell passage time using a Singlepore Erythrocytes Rigidometer (SER), showing pentoxifylline counteracts reduced cell flexibility.

    Area of Science:

    • Hematology
    • Biophysics
    • Pharmacology

    Background:

    • Red blood cell deformability is crucial for microcirculation.
    • Calcium (Ca2+) can impair red blood cell flexibility.
    • Pentoxifylline is a hemorheologic agent with potential effects on cell mechanics.

    Purpose of the Study:

    • To investigate the effect of pentoxifylline on human red blood cell deformability.
    • To assess pentoxifylline's efficacy in counteracting Ca2+-induced rigidity.

    Main Methods:

    • Human red blood cells were subjected to Ca2+ stress.
    • Red cell deformability was measured using a Singlepore Erythrocytes Rigidometer (SER).
    • The passage time of individual cells through a micropore was recorded under controlled pressure.

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    Related Experiment Videos

    Last Updated: Jan 21, 2026

    Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
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    Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

    Published on: January 12, 2018

    15.4K
    A Microfluidic Technique to Probe Cell Deformability
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    A Microfluidic Technique to Probe Cell Deformability

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    Main Results:

    • Ca2+ stress significantly increased the medium passage time (MPT), indicating reduced deformability (87.5 ms vs. 43.3 ms for control).
    • Pentoxifylline treatment of Ca2+-stressed red blood cells significantly reduced MPT (51.6 ms).
    • Pentoxifylline partially restored red blood cell deformability after Ca2+ challenge.

    Conclusions:

    • Pentoxifylline demonstrates a beneficial effect on red blood cell deformability under conditions of Ca2+ induced stress.
    • The findings suggest pentoxifylline may improve hemorheology in conditions where red blood cell rigidity is a factor.