Changes in the magnesium content of tissues following myocardial damage in rats

The magnesium content of blood, heart and striated muscle, liver, spleen, kidney and bone was determined in rats, 15, 30 and 60 minutes, 6 and 24 hours after isoprenaline induced myocardial damage. The magnesium concentration increased significantly in the serum (but not in the red cells) in the first three groups of animals, while the magnesium concentration of heart muscle fell in all groups. There was no evidence of magnesium flux in the other tissues.