Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Propoxyphene dependence: an update

G B Collins, K S Kiefer

    Postgraduate Medicine
    |December 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Propoxyphene (Darvon) carries a risk of addiction and withdrawal, contrary to early beliefs. Physicians need to be aware of its abuse potential and monitor patients closely.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Agrobacterium tumefaciens- mediated transformation of soybean [Glycine max (L.) Merrill.] using immature zygotic cotyledon explants.

    Plant cell reports·2019
    Same author

    Factors affecting soybean cotyledonary node transformation.

    Plant cell reports·2019
    Same author

    Development of a binary vector system for plant transformation based on the supervirulent Agrobacterium tumefaciens strain Chry5.

    Plant cell reports·2019
    Same author

    The role of nuclear fusion in pollen embryogenesis of Datura innoxia Mill.

    Planta·2014
    Same author

    Genetic parameters in aKy 14 xKy Ex 42 burley population ofNicotiana tabacum L.

    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2014
    Same author

    Genetic variation in tissue cultures of red clover.

    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
    Same journal

    Relationship of serum nesfatin-1 levels with body mass index and c-reactive protein in patients presenting to the emergency department with epileptic seizures.

    Postgraduate medicine·2026
    Same journal

    Clinical pharmacokinetics of colistimethate sodium and formed colistin in patients with renal impairment or on dialysis modalities: a systematic review and implications for precision dosing.

    Postgraduate medicine·2026
    Same journal

    The role of type D personality in pregnancy symptom severity, functional limitations, and maternal ambivalence.

    Postgraduate medicine·2026
    Same journal

    Operational and demographic predictors of leaving without being seen in a high-volume tertiary emergency department: a five-year case-control study.

    Postgraduate medicine·2026
    Same journal

    Risk of adverse effects of the concomitant use of statins with calcium channel blockers: a systematic review and meta-analysis.

    Postgraduate medicine·2026
    Same journal

    Association between frailty and major chronic disease-free life expectancy: a large community-based longitudinal study.

    Postgraduate medicine·2026
    See all related articles

    Area of Science:

    • Pharmacology
    • Addiction Medicine
    • Public Health

    Background:

    • Propoxyphene (Darvon) was initially marketed as an analgesic with low dependence risk.
    • International recognition of propoxyphene's addictive potential, including psychological and physical dependence, is increasing.

    Observation:

    • Physicians often remain unaware of propoxyphene's true addictive nature and abuse potential.
    • Propoxyphene is readily available via prescription and is less expensive than illicit opiates.

    Findings:

    • Propoxyphene poses a significant risk for abuse and addiction, despite potentially lower addiction frequency compared to other narcotics.
    • Documentation confirms both psychological dependence and physical withdrawal symptoms associated with propoxyphene use.

    Related Experiment Videos

    Implications:

    • Increased physician caution is warranted when prescribing propoxyphene.
    • Close monitoring of patients currently taking propoxyphene for signs of abuse or dependence is crucial.