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Fat tolerance test in pregnancy: Intralipid loading test

Hyperlipemia occurs during pregnancy. The present study deals with lipid metabolism in the female by comparing the response of the pregnant with that of non-pregnant females to a lipid loading test with 10% Intralipid given intravenously. The results were: (i) Exogenous and endogenous triglycerides (TG) were significantly higher inthe pregnant group. (ii) The K2 value was significantly lower in the pregnant group. (iii) The level of FFA in the non-pregnant group rose rapidly 5 min after Intralipid load. In contrast, the pregnant group showed a gradual rise which reached a maximum one hr after administration of Intralipid. The delay of the lipid metabolism during pregnancy might be one of the reason of hyperlipemia.

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