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Updated: Aug 1, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 12, 2014
Studies on human Laryngeal papilloma. Degeneration of lymphocytes within the neoplastic cells
Abstract:
Biopsies from 5 cases of Juvenile Laryngeal Papilloma were studied by electron microscopy. In 2 cases, phagocytosed neutrophils were seen in various stages of degeneration and disintegration within the neoplastic cells. The possible phenomenon of "emperiopolesis' and "phagocytosis' in a benign neoplasm is described, and it is suggested that all cases of Juvenile Laryngeal Papilloma must be carefully examined by light- and electron microscopy in an attempt to locate any phagocytic activity in the neoplastic cells which may provide evidence for the early detection of malignancy.
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