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Red blood cells coated with tumor cell extracts as targets in 51Cr release assays
Abstract:
Sheep red-blood cells were coated with tumor cell antigens prepared by extractions with 3M KCl. The coated cells were labelled with 51Cr and used as targets in immuno-assays. The technique was found suitable for complement-mediated as well as antibody-dependent cell-mediated reactions, and it offers several applications for use in tumor immunology.