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Renal infection and pregnancy outcome
American Journal of Obstetrics and Gynecology
|November 15, 1981
Summary
Treated renal infections, including asymptomatic bacteriuria and acute pyelonephritis in pregnant women, showed no significant adverse effects on pregnancy outcomes. Infant health and maternal complications were comparable between infected and non-infected groups.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Nephrology
Background:
- Renal infections during pregnancy can pose risks to both mother and fetus.
- Asymptomatic bacteriuria and acute pyelonephritis are common urinary tract infections in pregnant individuals.
Purpose of the Study:
- To evaluate the impact of asymptomatic renal bacteriuria and acute pyelonephritis on pregnancy outcomes.
- To determine if treated renal infections significantly alter maternal and infant health indicators.
Main Methods:
- Prospective matched study of 248 pregnant women with asymptomatic bacteriuria versus abacteriuric controls.
- Case-control study of 487 pregnant women with acute pyelonephritis.
- Antibody-coated bacteria method used for infection localization.
Main Results:
- No adverse effects observed in women with treated asymptomatic renal or bladder infections.
- Maternal hypertension and anemia rates were similar between infected and control groups.
- Infant outcomes (perinatal mortality, gestational age, birth weight, maturity) were comparable.
- Antepartum pyelonephritis did not increase adverse perinatal outcomes, but intrapartum infection was linked to premature labor in some cases.
Conclusions:
- Treated renal infections, whether symptomatic or asymptomatic, do not significantly modify overall pregnancy outcomes.
- While intrapartum pyelonephritis may contribute to premature labor, overall pregnancy health is not significantly impacted by treated renal infections.