Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Gardner's syndrome (author's transl)]

H Prache, C Tourin, M de Regnault

    Annales D'Oto-Laryngologie Et De Chirurgie Cervico Faciale : Bulletin De La Societe D'Oto-Laryngologie Des Hopitaux De Paris
    |January 1, 1981
    PubMed
    Summary

    Gardner's syndrome is an inherited condition affecting multiple germ layers, causing diverse symptoms. Early detection of any sign warrants a search for colon polyps due to cancer risk.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Family allergy in homozygosity.

    Annales de dermatologie et de syphiligraphie·2010
    Same author

    [Loperamide-induced acute pancreatitis].

    Gastroenterologie clinique et biologique·2000
    Same author

    Elective laparoscopic sigmoid colectomy for diverticulitis. Results of a prospective study.

    Surgical endoscopy·1999
    Same author

    Factors influencing long-term survival in 100 cases of small intestine primary adenocarcinoma.

    American journal of surgery·1997
    Same author

    [Acute intestinal intussusception in an adult treated by celioscopy].

    Gastroenterologie clinique et biologique·1995
    Same author

    [Laparoscopic cholecystectomy: technical gestures].

    Journal de chirurgie·1992

    Area of Science:

    • Genetics and Hereditary Diseases
    • Developmental Biology
    • Gastroenterology

    Background:

    • Gardner's syndrome is an autosomal dominant hereditary disorder.
    • It results from developmental abnormalities across ectoderm, endoderm, and mesoderm.
    • This syndrome presents with a wide spectrum of clinical manifestations.

    Observation:

    • Symptoms can involve Ear, Nose, and Throat (ENT) specialists, dermatologists, maxillo-facial surgeons, and gastroenterologists.
    • A growing recognition of partial or dissociated forms of Gardner's syndrome exists.
    • Isolated symptoms may indicate underlying polyposis.

    Findings:

    • The syndrome's multi-germ layer origin explains its diverse pathology.
    • Identifying a single Gardner's symptom necessitates a thorough investigation for colorectal polyposis.
    • Colorectal polyposis is a significant risk factor for malignant transformation.

    Implications:

    • Prompt diagnosis of Gardner's syndrome is crucial for patient management.
    • Systematic screening for colon polyps in affected individuals can improve prognosis.
    • Understanding the syndrome's genetic basis aids in risk assessment and potential therapeutic strategies.

    Related Experiment Videos