Serum uric acid in Jordanian Arabs

Area of Science:

• Biochemistry
• Human Physiology
• Population Health

Background:

• Serum uric acid levels are a key indicator of metabolic health.
• Previous studies have established reference ranges in various populations.
• Understanding population-specific variations is crucial for accurate health assessments.

Purpose of the Study:

• To determine reference ranges for serum uric acid in healthy Jordanian Arabs.
• To investigate the distribution patterns of serum uric acid in this population.
• To explore correlations between serum uric acid and anthropometric parameters.

Main Methods:

• Serum uric acid levels were measured in 96 males and 140 females.
• Frequency histograms were used to analyze data distribution.
• Correlations with age, height, body weight, ponderal index, and total body surface area were assessed.

Main Results:

• Serum uric acid values were comparable to those reported in the US and UK.
• Frequency distributions for serum uric acid were not normally distributed, with a hint of bimodality observed.
• Significant positive correlations were found between serum uric acid and ponderal index (P<0.05) and total body surface area (P<0.001).

Conclusions:

• Serum uric acid reference ranges in Jordanian Arabs align with Western values.
• The non-normal distribution suggests potential underlying factors influencing uric acid levels.
• Ponderal index and body surface area are significant predictors of serum uric acid in this cohort.