Glycerol dehydration tests in Ménière's disorder using extratympanic electrocochleography

Eleven patients with classical Ménière's disorder were examined electrophysiologically using extratympanic electrocochleography. All had been fully investigated audiologically and by electronystagmography. In addition to the classical triad of symptoms, 7 complained also of fullness or blockage in the ear, this symptoms being associated with fluctuation of the deafness. All patients showed the characteristic enhancement of the SP component of the AP/SP waveform. Following glycerol the SP component was reduced in amplitude, producing a decrease in the width of the waveform. Maximum reduction occurred approximately 60 min after administration of glycerol.