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Related Experiment Videos

Metoprolol and alopecia

C W Graeber, R A Lapkin

    Cutis
    |December 1, 1981
    PubMed
    Summary

    Beta-blockers like metoprolol can cause reversible hair loss. A case study confirmed this hair thinning, known as telogen effluvium, suggesting a shared side effect among these hypertension medications.

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    Area of Science:

    • Pharmacology
    • Dermatology
    • Cardiology

    Background:

    • Beta-adrenoceptor antagonists are widely prescribed for managing hypertension.
    • Propranolol, a common beta-blocker, has been linked to reversible alopecia (hair loss).
    • The specific type of hair loss observed is telogen effluvium.

    Observation:

    • This report details a patient experiencing reversible alopecia.
    • The patient was treated with metoprolol (Lopressor), another beta-blocker.
    • Scalp biopsy confirmed the presence of telogen effluvium.

    Findings:

    • Metoprolol, similar to propranolol, can induce reversible telogen effluvium.
    • The findings suggest a common mechanism for hair loss induced by beta-adrenergic antagonists.
    • This adverse effect is characterized by diffuse, non-scarring hair shedding.

    Implications:

    • Clinicians should be aware of potential hair loss as a side effect of metoprolol.
    • Early recognition and management of drug-induced alopecia can improve patient adherence.
    • Further research may elucidate the precise molecular pathways involved in beta-blocker-induced alopecia.

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