Blood pressure in stroke-prone SHR (SHRSP) exposed to unusual environmental temperature

1) It is generally accepted that the adequate environmental temperature to rear rats is about 23 degrees C, but the adequate temperature that directly contacts to the animal's skin seems to be about 30 degrees C. 2) The blood pressure increased on cold exposure or stimulation. There was a case that the blood pressure increased slightly on hot exposure. This suggests that it is necessary to pay close attention to the condition of warming-up at the indirect measurement of blood pressure. 3) Apoplexy seemed to occur earlier at the low environmental temperature, and the blood pressure seemed to increase also at the high temperature. However, these temperature effects on blood pressure and the incidence of stroke were not so obvious as observed in rearing SP with 0.9% salt solution for drinking.