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Mortality among ethylene oxide workers

R W Morgan, K W Claxton, B J Divine

Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association

|November 1, 1981

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A mortality study of 767 male workers exposed to ethylene oxide found no leukemia deaths. The study observed fewer deaths than expected, indicating no increased mortality risk from this chemical exposure.

Area of Science:

Occupational Health
Toxicology
Epidemiology

Background:

Reports suggest a link between ethylene oxide exposure and increased leukemia risk.
Assessing occupational health risks is crucial for worker safety.

Purpose of the Study:

To investigate the mortality risk, specifically leukemia, in workers with potential ethylene oxide exposure.
To evaluate the overall mortality experience of a cohort exposed to ethylene oxide.

Main Methods:

A cohort mortality study was conducted.
Identified 767 male workers with potential ethylene oxide exposure at a chemical plant.
Compared observed deaths to expected deaths using standardized mortality ratios (SMR).

Main Results:

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A total of 46 deaths occurred in the cohort, compared to 80 expected deaths (SMR = 58).
No deaths from leukemia were observed.
No statistically significant excesses in mortality were found for any specific causes of death.

Conclusions:

The study found no evidence of increased leukemia risk or overall mortality among workers exposed to ethylene oxide.
The observed mortality was lower than expected, suggesting no adverse health effects from occupational exposure in this cohort.