[Ultrastructural changes in the aorta following damage to the transport through the vessel wall]

Be the ligature of lymphatic vessels lymphostasis has been produced and the consequences of it in the myocardium were studied. Lymphatics of the myocardium in lymphostasis were compared with those in the normal one. It was found that the space between lymphatics and myocardial fibers filled mainly with connective tissue due to accumulation of oedema fluid enlarges and the collagen fibers disintegrate. At the same time accumulation of fluid and dilatation of lymphatics takes also place. Pinocytotic activity of endothelial cells increases. Due to oedema vacuolization of myocardial cells occurs. Disturbance of the capillary circulation leads to swelling of endothelial cells and narrowing the capillary lumen. This lies on the basis of hypoxia and fatty degeneration of the myocardium. The coronary vessels have also shown alterations. In the subendothelial space accumulation of plasma constituents, in the smooth muscle cells of the vessel wall oedema was found. Thus, lymphostasis in the myocardium results in significant alterations.