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Related Experiment Videos

Focal prostatic granulomas. A sequel to transurethral resection

H Hedelin, S Johansson, S Nilsson

    Scandinavian Journal of Urology and Nephrology
    |January 1, 1981
    PubMed
    Summary

    Prostatic granulomas can occur after transurethral prostatic resection, presenting with voiding issues or hematuria. These granulomas, characterized by necrosis and eosinophilic infiltrates, are often misdiagnosed but appear self-limiting.

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    Area of Science:

    • Urology
    • Pathology
    • Surgical Complications

    Background:

    • Transurethral prostatic resection (TURP) is a common procedure for benign prostatic hyperplasia.
    • Complications following TURP can include inflammation and granuloma formation.
    • The etiology and clinical significance of prostatic granulomas post-TURP require further elucidation.

    Purpose of the Study:

    • To describe the clinical and histologic features of prostatic granulomas after TURP.
    • To investigate potential etiologic factors, such as bacteriuria.
    • To highlight diagnostic challenges and the clinical course of this condition.

    Main Methods:

    • Retrospective review of 6 cases with prostatic granuloma post-TURP.
    • Analysis of clinical presentations, including indications for repeat surgery.

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  • Histopathologic examination of resected prostatic tissue.

    • Main Results:

    • Prostatic granulomas were observed 1 week to 14 months after initial TURP.
    • Symptoms included severe urgency, voiding difficulty, and persistent hematuria.
    • Histology revealed fibrinoid necrosis; eosinophilic infiltrates were present in 3 cases.
    • Bacteriuria was not found to be a significant etiologic factor.
    • Initial diagnoses included specific inflammation mimicking tuberculosis in 3 patients.

    Conclusions:

    • Prostatic granulomas are a recognized, though not widely, complication of TURP.
    • The condition appears self-limiting, but its association with persistent hematuria is clinically relevant.
    • Accurate histopathologic diagnosis is crucial to avoid misclassification, particularly with granulomatous inflammation.