Related Experiment Video
Updated: Aug 12, 2026
06:25
Chromosomics: Detection of Numerical and Structural Alterations in All 24 Human Chromosomes Simultaneously Using a Novel OctoChrome FISH Assay
Published on: February 6, 2012
[Chromosome aberrations in a lymphocyte culture from persons in contact with chromium]
Tsitologiia I Genetika
|November 1, 1981
Abstract:
A detailed analysis was carried out of chromosome aberrations induced by chromium compounds in a lymphocyte culture of persons which were in contact with the compounds. It is shown that the frequency of cells with chromosome aberrations depends on the age and duration of contact with chromium and does not depend on the sex. It was marked that hexavalent chromium compounds have a higher cytogenetic activity. Mechanisms of mutagenic action of heavy metal ions are discussed (taking chromium as an example).
Related Concept Videos
01:17Karyotyping
Describing the number and physical features of chromosomes can reveal abnormalities that underlie genetic diseases. This description is facilitated by special staining techniques that produce a particular banding pattern on each chromosome. State-of-the-art techniques make this approach even more powerful, enabling the detection of individual genes that cause disease.A Simple Chromosome Staining Technique Provides Valuable Scientific InsightSome genetic diseases can be detected by looking at...
01:51Lampbrush Chromosomes
In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops resemble the...
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops resemble the...