[Pathogenesis and diagnosis of progressive neuromuscular diseases]

On the basis of literary data and his own observations the author discusses the mechanisms of the development of progressing muscular dystrophies and methods of their diagnosis. A critical analysis of the principal modern concepts of the origin of the progressing myodystrophies (the myogenic, membrane, vascular, connective-tissue, and neurogenic ones) is presented. The results of biochemical diagnostic tests are summed up, and the importance of examining various enzymes for the verification of the disease early stages is stressed.