Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiovascular changes during controlled blood loss and replacement

T Kirwan, C F Scurr, G B Smith

    Anaesthesia
    |December 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Observational study of the relationship between nurse staffing levels and compliance with mandatory nutritional assessments in hospital.

    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2021
    Same author

    Vital signs and other observations used to detect deterioration in pregnant women: an analysis of vital sign charts in consultant-led UK maternity units.

    International journal of obstetric anesthesia·2017
    Same author

    Heap leach cyanide irrigation and risk to wildlife: Ramifications for the international cyanide management code.

    Ecotoxicology and environmental safety·2017
    Same author

    Comparison of the National Early Warning Score in non-elective medical and surgical patients.

    The British journal of surgery·2016
    Same author

    Introduction of an electronic physiological early warning system: effects on mortality and length of stay.

    British journal of anaesthesia·2015
    Same author

    'Errors' and omissions in paper-based early warning scores: the association with changes in vital signs--a database analysis.

    BMJ open·2015
    Same journal

    Pulmonary artery catheters or central venous catheters for cardiac surgery: the PUMA Pilot randomised clinical trial.

    Anaesthesia·2026
    Same journal

    Opioid-free vs. opioid-inclusive anaesthesia with or without regional anaesthesia for postoperative pain.

    Anaesthesia·2026
    Same journal

    Optimal dose of intra-operative dexmedetomidine for postoperative delirium prevention: a reply.

    Anaesthesia·2026
    Same journal

    Optimal dose of intra-operative dexmedetomidine for postoperative delirium prevention.

    Anaesthesia·2026
    Same journal

    Pain control or brain protection with esketamine: a reply.

    Anaesthesia·2026
    Same journal

    A step forward for patient-centred fasting guidelines: a reply.

    Anaesthesia·2026
    See all related articles

    Central venous pressure monitoring effectively indicates blood loss and replacement during surgery. However, precise blood volume changes could not be numerically correlated with central venous pressure readings.

    Area of Science:

    • Anesthesiology
    • Cardiovascular Physiology
    • Surgical Monitoring

    Background:

    • Accurate monitoring of hemodynamic status is crucial during major surgical procedures.
    • Blood loss and volume replacement significantly impact patient hemodynamics.
    • Central venous pressure (CVP) is a commonly used parameter to assess fluid status.

    Purpose of the Study:

    • To evaluate the utility of central venous pressure (CVP) in monitoring blood loss and transfusion during surgery.
    • To investigate the correlation between blood volume changes and CVP.
    • To compare hemodynamic responses between different anesthetic ventilation methods.

    Main Methods:

    • 31 patients undergoing surgery with 1-liter blood withdrawal and transfusion were studied.
    • Central venous pressure, systolic arterial pressure, and pulse rate were continuously monitored.

    Related Experiment Videos

  • Patients were anesthetized using either spontaneous ventilation with halothane or intermittent positive pressure ventilation.

    • Main Results:

    • Central venous pressure provided immediate and consistent indications of blood loss and replacement.
    • A numerical correlation between blood volume changes and central venous pressure was not established.
    • No significant differences in hemodynamic parameters were observed between the two ventilation groups.

    Conclusions:

    • Central venous pressure is a valuable real-time indicator of acute blood loss and transfusion effectiveness.
    • While CVP reflects volume status changes, it does not allow for precise numerical quantification of blood volume.
    • Anesthetic ventilation strategy (spontaneous vs. intermittent positive pressure ventilation) did not impact the observed hemodynamic responses in this context.