[Changes in heart structure in intrapericardial stenosis of the pulmonary trunk]

Dynamics of decompensatory changes in the heart (in cardiomyocytes, connective tissue stroma of the myocardium, neural structures, microcirculatory bed) has been followed under conditions of developing stenosis of the pulmonary trunk. The data have been obtained by means of various investigational methods: histological - injection of vessels with Indian ink - gelatin, impregnation of the neural structures after Bielschowsky - Gros; histochemical - to reveal functional activity of parasympathetic and sympathetic neural structures after Koelle - Gomori and Falck - Hillarp - Govyrin, and electronmicroscopically. At the beginning of the experiment destructive processes predominate. By the first month, compensatory-adaptive processes develop in the heart. By the first year, persisting hypoxia and quick exhaustion of all cardiac structures result in development of the heart failure.