Removal of endogenous lactates via the peritoneum in experimental lactic acidosis

Peritoneal dialysis was used in experimental lactic acidosis caused by hypoxia for the removal of endogenous lactate. Two types of dialysis fluid, with and without vasodilator sodium nitroprusside, added intraperitoneally were used. The addition of sodium nitroprusside increased peritoneal the clearance of lactate as did an alkaline dialysis fluid containing bicarbonate. The highest clearance values were observed when alkaline dialysis fluid was used together with sodium nitroprusside.