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Updated: Aug 1, 2026

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A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique
Published on: April 26, 2015
A model of ventricular fibrillation in the isolated rat heart
Journal of Pharmacological Methods
|November 1, 1981
Abstract:
A simple technique is described for the induction of reversible ventricular fibrillation in the isolated rat heart. Fibrillation is induced by doubling the calcium chloride and halving the sodium chloride concentration of the perfusate. Fibrillation can be prevented by Class I antiarrhythmic drugs and verapamil.

