Cross cellular contamination in plateletpheresis, leukapheresis and plasma exchange

Continuous flow cell separation procedures in the IBM-2997 single stage and dual stage channels allow collection of components for replacement transfusions and therapeutic exchange of plasma or depletion of leukemic leukocytoses or thrombocytoses. Minimal cross cellular contamination with red cells and lymphocytes is achieved for platelets collected in the dual stage channel through blood path design. A reduction in cross cellular contamination is minimized in the single stage channel by procedural guidelines which reflect the principles of whole blood response to centrifugal acceleration in this system