[The evaluation of bone changes in beta-thalassaemias by xeroradiography (author's transl)]

A xeroradiographic investigation of the skull, hand and elbow bones were carried out by the authors in 50 patients with beta-thalassemia major and in 14 with beta-thalassaemia intermedia. The results were extensively compared with x-ray images. The xeroradiographic method, for its edge contrast enhancement effect and great latitude, better documented than x-ray widening of the medullary cavities and cortex thinness in the shaft of long bones. The diploic space of the skull appeared more detailed; the "hair-brush" pattern and outer table were also particularly demonstrated. The use of "positive mode" imaging is the main requirement in the study of skull and extremities. The changes observed with xeroradiography were statistically more characterized than that seen with x-ray, enhancing the evolution of bone involvement due to actual longer survival of these patients.