Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Post-transfusion hepatitis]

I Serban, V Gorgan, C Onesciuc

    Revista De Igiena, Bacteriologie, Virusologie, Parazitologie, Epidemiologie, Pneumoftiziologie. Bacteriologia, Virusologia, Parazitologia, Epidemiologia
    |July 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Estimating the incidence of COVID-19 skin manifestations on the general population in a territorial setting.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2022
    Same author

    Facial seborrheic keratosis with unusual dermoscopic patterns can be differentiated from other skin malignancies by in vivo reflectance confocal microscopy.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2021
    Same author

    [Etiology of ventilator-associated pneumonia at the Cardiovascular Surgery Clinic of Iaşi].

    Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2012
    Same author

    [Fungi as emergent etiologic agents in ventilator-associated pneumonia after cardiac surgery].

    Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2011
    Same author

    Domain wall in a chiral p-wave superconductor: a pathway for electrical current.

    Physical review letters·2010
    Same author

    Optimal control of a qubit coupled to a non-Markovian environment.

    Physical review letters·2009

    Preventing post-transfusion hepatitis (PTH) through careful donor screening and transfusion practices significantly reduced its incidence. Early detection of Hepatitis B carriers is crucial for preventing PTH type B, which is costly to treat.

    Area of Science:

    • Hepatology
    • Transfusion Medicine
    • Virology

    Background:

    • Post-transfusion hepatitis (PTH) posed a significant challenge in acute viral hepatitis management.
    • Hepatitis B virus (HBV) was identified as a major contributor to PTH.
    • The economic burden of PTH treatment exceeded that of general acute viral hepatitis.

    Purpose of the Study:

    • To investigate the incidence, etiology, evolution, prognosis, and treatment of PTH.
    • To evaluate the impact of transfusion practices and HBV carrier screening on PTH frequency.
    • To determine the proportion of PTH attributed to Hepatitis B and advocate for improved detection methods.

    Main Methods:

    • Retrospective analysis of 253 PTH cases among 7224 acute viral hepatitis patients (1973-1979).

    Related Experiment Videos

  • Implementation of rational transfusion protocols and HBV carrier elimination strategies.
  • Donor screening using contra-immunoelectrophoresis to detect Hepatitis B surface antigen (HBs Ag).

    • Main Results:

    • A three-fold decrease in PTH incidence was observed following improved transfusion practices and HBV carrier control.
    • Hepatitis B accounted for at least 26.8% of all PTH cases.
    • PTH treatment was complex, requiring prolonged hospitalization and incurring higher costs than general acute viral hepatitis.

    Conclusions:

    • Rational transfusion and HBV carrier elimination are effective in reducing PTH incidence.
    • More sensitive HBs Ag detection methods are necessary to eliminate PTH type B.
    • Investment in PTH prevention is cost-effective due to the high treatment expenses.