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Updated: Aug 14, 2026

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Influenza A Virus Studies in a Mouse Model of Infection
Published on: September 7, 2017
The effect of sodium fluoride on experimental influenza virus infection in mice
Virologie
|October 1, 1981
Abstract:
NaF was administered intranasally to mice, either as a single 0.1-ml dose (containing 100 gamma), one hour before inoculation of influenza virus A/PR8/34 (H0N1), or as four similar daily doses, the last drug application preceding virus inoculation by 1 hour. In both cases the drug treatment led to a marked reduction in the hemagglutinating titers recorded in lung suspensions, accompanied by a lower mortality percentage and by an increase in mean survival length.
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