Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

HDL levels in Pacific islanders

P J Nestel, P Zimmet

    Atherosclerosis
    |November 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    South Pacific Islanders have lower high density lipoprotein (HDL) levels than Australians, but also less coronary heart disease (CHD). Urbanization and diet influence HDL concentrations, but not CHD prevalence in these populations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The effects of dietary weight loss with or without exercise training on liver enzymes in obese metabolic syndrome subjects.

    Diabetes, obesity & metabolism·2011
    Same author

    Circulating inflammatory and atherogenic biomarkers are not increased following single meals of dairy foods.

    European journal of clinical nutrition·2011
    Same author

    Dietary supplementation with chickpeas for at least 5 weeks results in small but significant reductions in serum total and low-density lipoprotein cholesterols in adult women and men.

    Annals of nutrition & metabolism·2006
    Same author

    Fish oils, phytosterols and weight loss in the regulation of lipoprotein transport in the metabolic syndrome: lessons from stable isotope tracer studies.

    Clinical and experimental pharmacology & physiology·2006
    Same author

    Dairy fat in cheese raises LDL cholesterol less than that in butter in mildly hypercholesterolaemic subjects.

    European journal of clinical nutrition·2005
    Same author

    The isoflavone metabolite dehydroequol produces vasodilatation in human resistance arteries via a nitric oxide-dependent mechanism.

    Atherosclerosis·2004

    Area of Science:

    • Cardiovascular Epidemiology
    • Lipid Metabolism
    • Population Health

    Background:

    • High density lipoprotein (HDL) cholesterol concentration is a key indicator of coronary heart disease (CHD) risk in Caucasian populations.
    • Limited data exists on HDL level variations across populations with differing CHD prevalence.
    • Apolipoprotein AI (ApoAI) is the primary protein component of HDL.

    Purpose of the Study:

    • To compare apolipoprotein AI (ApoAI) concentrations among South Pacific Islanders of diverse ethnic backgrounds.
    • To investigate the relationship between urbanization, diet, and ApoAI levels in Polynesian men.
    • To assess the correlation between ApoAI levels and the prevalence of probable CHD in Western Samoan men.

    Main Methods:

    • Measurement of apolipoprotein AI (ApoAI) concentrations in Melanesian and Polynesian men on Ouvea.

    Related Experiment Videos

  • Comparison of ApoAI levels between rural and urbanized Polynesian men in Western Samoa.
  • Electrocardiographic assessment of probable CHD prevalence in Western Samoan men aged 40-69.
  • Survey of dietary and lifestyle factors influencing HDL levels.

    • Main Results:

    • Mean ApoAI levels in Melanesian and Polynesian men on Ouvea were significantly lower (94 and 91 mg/dl) compared to Australian men (120 +/- 20 mg/dl).
    • Urbanization in Western Samoa led to increased ApoAI levels in Polynesian men (117 mg/dl in town vs. 94 mg/dl in village).
    • Dietary factors, including fat and alcohol intake, were associated with higher ApoAI levels.
    • Probable CHD prevalence in Western Samoan men was approximately half that of Australian men, despite lower ApoAI levels.

    Conclusions:

    • Lower apolipoprotein AI (ApoAI) levels in Western Samoan men are not directly correlated with a higher prevalence of coronary heart disease (CHD).
    • Urbanization and dietary changes, particularly increased fat and alcohol consumption, appear to elevate ApoAI levels.
    • Further research is needed to elucidate the complex interplay between HDL, ApoAI, diet, and CHD risk in diverse populations.