Related Experiment Videos
Percutaneous absorption of zinc in acrodermatitis enteropathica
Dermatologica
|January 1, 1981
Insights
Topical zinc oxide paste rapidly improved acrodermatitis enteropathica symptoms in an infant. This treatment offers a promising localized therapy for this genetic zinc deficiency disorder.
Area of Science:
- Dermatology
- Pediatrics
- Medical Case Study
Background:
- Acrodermatitis enteropathica is a rare genetic disorder causing zinc malabsorption.
- Infantile zinc deficiency can manifest with severe skin lesions, particularly in the diaper area.
Observation:
- An 8-month-old female infant presented with symptoms of acrodermatitis enteropathica.
- The patient's diaper area exhibited characteristic skin lesions associated with the condition.
Findings:
- Local application of 25% zinc oxide paste was administered to the affected diaper area.
- Significant clinical improvement in the skin lesions was observed within one week of treatment initiation.
Implications:
- Topical zinc oxide demonstrates efficacy in managing localized symptoms of acrodermatitis enteropathica.
- This case highlights a potentially effective and accessible therapeutic option for infantile zinc deficiency dermatoses.
Abstract:
An 8-month-old girl with acrodermatitis enteropathica was treated with 25% zinc oxide paste, locally, in the diaper area. A rapid improvement of the symptoms was observed a week after initiation of the treatment.