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The molecular electrostatic potential and steric accessibility of poly (dI.dC). Comparison with poly (dG.dC)
Nucleic Acids Research
|December 21, 1981
Abstract:
The influence of the amino group of guanine on the molecular electrostatic potential and the accessibility to reactive sites of B-DNA is investigated by comparing the two model double helices poly (dI.dC) and poly (dG.dC). The calculations clarify the "disruptive" role of the guanine amino group on nucleic acid-polypeptide interactions.