Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hepatic biopsy in acute leukemia]

A Aviles Miranda, J Aguirre García, G Conte Lanza

    Revista De Gastroenterologia De Mexico
    |October 1, 1981
    PubMed
    Summary

    Liver biopsy in acute leukemia patients helps identify drug-induced hepatitis, guiding treatment modifications and improving patient outcomes. This diagnostic tool aids in managing chemotherapy

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Next generation sequencing in bleeding disorders: two novel variants in the F5 gene (Valencia-1 and Valencia-2) associated with mild factor V deficiency.

    Journal of thrombosis and thrombolysis·2019
    Same author

    Frequency and clinical impact of CDKN2A/ARF/CDKN2B gene deletions as assessed by in-depth genetic analyses in adult T cell acute lymphoblastic leukemia.

    Journal of hematology & oncology·2018
    Same author

    Letter to the Editor.

    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2018
    Same author

    Impact of NADPH oxidase functional polymorphisms in acute myeloid leukemia induction chemotherapy.

    The pharmacogenomics journal·2017
    Same author

    Energy transduction and signal averaging of fluctuating electric fields by a single protein ion channel.

    Physical chemistry chemical physics : PCCP·2016
    Same author

    The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes.

    Blood cancer journal·2015

    Area of Science:

    • Hepatology
    • Oncology
    • Diagnostic Pathology

    Context:

    • Acute leukemia patients often exhibit altered liver function tests.
    • Liver biopsies are crucial for diagnosing the cause of these abnormalities.
    • Evaluating treatment side effects is essential for patient management.

    Purpose:

    • To determine the nature of liver lesions in acute leukemia patients.
    • To assess the utility of hepatic biopsy in managing treatment-related liver complications.
    • To inform therapeutic decisions based on biopsy findings.

    Summary:

    • Twenty-nine liver biopsies were performed on 25 acute leukemia patients with abnormal liver function tests.
    • Results showed leukemic infiltration in one, nonspecific changes in 16, and drug-induced hepatitis in five patients.

    Related Experiment Videos

  • Drug-induced hepatitis necessitated chemotherapy modification, impacting survival times.

    • Impact:

    • Hepatic biopsy is valuable for detecting adverse treatment effects in acute leukemia.
    • Biopsy findings guide therapeutic decisions, potentially altering chemotherapy regimens.
    • The procedure's risks and contraindications are comparable to those in non-leukemia patients.