[Cross protection in mice immunized with different anti-influenza preparations]

Observations in white mice demonstrated the development of resistance to influenza type A virus (H3N2 and H0N1) after vaccination against influenza A (H1N1). The most marked cross protection between these serotypes developed after combined use of inactivated and live moderately attenuated vaccines. The resistance to the homologous influenza A (H1N1) virus after vaccination with different influenza vaccines used by various schedules was approximately similar. The role of common antigens and cellular factors of immunity in the development of cross protection against influenza type A viruses is discussed.