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Related Experiment Videos

Vasectomy: subclinical pathologic changes

J B Taxy, F F Marshall, R J Erlichman

    The American Journal of Surgical Pathology
    |December 1, 1981
    PubMed
    Summary
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    Vasectomy can cause local tissue changes like inflammation and granulomas in the vas deferens. Vasitis nodosa, a specific ductular proliferation, is a common finding in men experiencing infertility after vasectomy.

    Area of Science:

    • Urology
    • Pathology

    Background:

    • Vasectomy is a common sterilization procedure.
    • Secondary infertility can occur after vasectomy.
    • Histopathologic changes in the vas deferens following vasectomy are not fully characterized.

    Purpose of the Study:

    • To describe the local histopathologic changes in the vas deferens after vasectomy.
    • To identify specific lesions associated with post-vasectomy infertility.

    Main Methods:

    • Histopathologic examination of surgically excised vas deferens segments.
    • Analysis of tissue from patients undergoing vasovasostomy for secondary infertility.
    • Study of tissue from patients undergoing scrotal exploration for primary infertility.

    Main Results:

    Keywords:
    BiologyDemographic FactorsFamily PlanningHistology--changesLongterm EffectsMale SterilizationMale Urologic SurgeryPopulationPopulation DynamicsReversible SterilizationSterilization ReversalSterilization, SexualSurgeryTime FactorsTreatmentUrogenital SurgeryVas ReanastomosisVasectomy

    Related Experiment Videos

    • Fifty of 76 vas deferens segments showed inflammatory or proliferative changes.
    • Common findings included suture granuloma, sperm granuloma, and vasitis nodosa.
    • Vasitis nodosa, characterized by ductular proliferation, occurred in 66% of patients and is a significant finding.

    Conclusions:

    • Histopathologic changes, including vasitis nodosa, are common after vasectomy.
    • These changes may contribute to infertility in some men.
    • Recognition of vasitis nodosa is important in the context of post-vasectomy infertility evaluation.