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Updated: Aug 15, 2026

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
Published on: March 17, 2016
[Estradiol receptor in relation to clinical parameters of mammary tumor patients (author's transl)]
Abstract:
Various clinical parameters, as menopausal state of the patients, clinical staging, tumor histology, free interval and survival time are valid for assessment of mammary carcinomas in relation to prognosis and therapeutic regimens. A correlation between receptor status of the tumors and these parameters shows with some exceptions that the percentage of receptor positive tumors is higher in such cases which are representative for a favourable prognosis. Thus the receptor status is an additional marker to evaluating the prognosis of mammary tumor patients. To perform therapeutic regimens it is important that in nearly 67% of all cases repeated receptor investigations in tumor recurrences show the same results as investigations of the corresponding primary tumors do.

