[Studies on the function of maintaining concentration (TAF)--evaluation of clinical symptoms (author's transl)]

The function of maintaining concentrations (TAF) test was performed in patients with schizophrenia and hepatitis, and subjects with sleep deprivation. The results obtained are as follows: 1) Schizophrenia: It was suggested that TAF provided a reliable index of the effect and the amount of medicine as well as remissive condition. 2) Hepatitis: TAF tended to parallel the conditions of both acute and chronic hepatitis. A positive correlation was found between TAF-deviation (D) and gamma-glutamyl transpeptidase as well as lactate dehydrogenase (r = 0.682, 0.535, respectively). No significant correlation was found between TAF-level (L) and hepatic enzymes. 3) TAF-D of a 4-hour sleep group decreased significantly compared with that of a 8-hour sleep group. The lapse phenomenon of TAF curved line was observed in a 4-hour sleep group after 49 hours of sleep deprivation. It was considered that TAF was an objective index of pathological or physiological conditions.