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[The perverted nystagmus (author's transl)]

M Toupet, P Pialoux

    Annales D'Oto-Laryngologie Et De Chirurgie Cervico Faciale : Bulletin De La Societe D'Oto-Laryngologie Des Hopitaux De Paris
    |January 1, 1981
    PubMed
    Summary

    Perverted nystagmus, a sign of central or peripheral vestibular disorders, often indicates brainstem involvement. This eye movement abnormality can help localize neurological issues during vestibular testing.

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    Area of Science:

    • Neurology
    • Ophthalmology
    • Vestibular System

    Context:

    • Perverted nystagmus modifies horizontal nystagmus with vertical or rotatory components.
    • It can be experimentally induced by unilateral destruction of vestibular nuclei.

    Purpose:

    • To analyze 32 cases of perverted nystagmus and identify its underlying causes and diagnostic significance.
    • To investigate the association between perverted nystagmus and central versus peripheral vestibular disorders.

    Summary:

    • 75% of subjects with perverted nystagmus had central diseases, while 20% had vestibular neuronitis.
    • Abnormal responses during caloric testing were frequent (95%), often showing canal paresis on one side and hyperreflexia on the other.
    • The study suggests a loss of inhibitory control on superior semicircular canal activity as a potential cause.

    Impact:

    • Perverted nystagmus is a valuable clinical sign for diagnosing brainstem topography.
    • It aids in differentiating central from peripheral vestibular disorders, including vestibular neuronitis.

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