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Cardiac involvement in polymyositis

M Oka, T Raasakka

    Scandinavian Journal of Rheumatology
    |January 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Cardiac involvement is common in polymyositis (PM), affecting 69% of patients. Heart disease in PM, including arrhythmias and heart failure, is a poor prognostic sign, often leading to fatal outcomes.

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    Area of Science:

    • Cardiology
    • Neurology
    • Rheumatology

    Background:

    • Polymyositis (PM) is an idiopathic inflammatory myopathy.
    • Cardiac involvement is a known complication of PM, but its prevalence and impact require further elucidation.

    Purpose of the Study:

    • To investigate the incidence and types of cardiac involvement in patients with polymyositis.
    • To assess the prognostic significance of cardiac complications in polymyositis.

    Main Methods:

    • Retrospective analysis of 16 polymyositis cases treated at a central hospital.
    • Review of patient records for cardiac manifestations, including electrocardiography (ECG) and clinical outcomes.
    • Autopsy findings were examined in relevant cases.

    Main Results:

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    • Cardiac involvement was observed in 11 out of 16 (69%) polymyositis patients.
    • Manifestations included conduction disturbances, congestive heart failure, and coronary heart disease.
    • Three patients experienced acute myocardial infarction; four cases of congestive heart failure were fatal.
    • ECG showed arrhythmias in eight patients and conduction disturbances in three.

    Conclusions:

    • Cardiac involvement is highly prevalent in polymyositis.
    • Heart disease in polymyositis patients is associated with a poor prognosis and increased mortality.
    • Early detection and management of cardiac complications are crucial in polymyositis care.