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Some hygienic and clinical observations on styrene exposure
Scandinavian Journal of Work, Environment & Health
|January 1, 1978
Summary
Workers in small shops manufacturing plastic products showed high styrene exposure. Monitoring mandelic acid in urine proved effective for exposure control, despite observed nervous system effects.
Area of Science:
- Occupational Health
- Industrial Hygiene
- Toxicology
Background:
- Styrene is a volatile organic compound used in manufacturing glass fiber reinforced plastics.
- Workers in small manufacturing shops may face significant exposure to styrene.
- Previous studies indicated potential health risks associated with styrene exposure.
Purpose of the Study:
- To assess styrene exposure levels in small plastic product manufacturing facilities.
- To evaluate the effectiveness of mandelic acid monitoring for exposure control.
- To investigate potential health effects in exposed workers.
Main Methods:
- Air sampling to measure styrene concentration (8-h time-weighted average).
- Biomonitoring of workers through urinary mandelic acid determination.
- Clinical observation for neurological and liver function indicators.
Main Results:
- Styrene exposure levels ranged from 100--300 ppm.
- Urinary mandelic acid monitoring was found to be a suitable and convenient method for exposure assessment.
- Central nervous system disturbances were observed in some workers.
- Elevated amino-transferase levels were recorded, with uncertain long-term liver implications.
Conclusions:
- Styrene exposure in small plastic manufacturing settings can be substantial.
- Mandelic acid monitoring is a practical tool for managing occupational styrene exposure.
- Observed health effects, including neurological disturbances, warrant continued attention and potential intervention.