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Related Experiment Videos

Fatal jaundice in pregnancy

J R Parkes

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |September 2, 1978
    PubMed
    Summary

    A hepatitis A virus epidemic caused jaundice in pregnant women in South Africa, leading to high mortality initially. The outbreak

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    Area of Science:

    • Hepatology
    • Epidemiology
    • Virology

    Background:

    • A severe epidemic of jaundice affected pregnant women.
    • High mortality rates were observed during the initial phase of the outbreak.

    Purpose of the Study:

    • To investigate the cause of the jaundice epidemic in pregnant women.
    • To understand the epidemiological characteristics of the outbreak.

    Main Methods:

    • Biochemical investigations were conducted.
    • Social and epidemiological data were collected and analyzed.

    Main Results:

    • The mortality rate was 45% in the first two years.
    • The mortality decreased as the epidemic subsided.
    • Hepatitis group A virus was identified as the probable causative agent.

    Conclusions:

    • The epidemic was likely caused by Hepatitis A virus.
    • This appears to be the first recorded epidemic of its kind in South Africa.