[Does oral contraception cause deep venous thromboses? (author's transl)]

Area of Science:

• Vascular Surgery
• Thrombosis Research
• Pharmacological Risk Assessment

Context:

• A retrospective analysis of 48 women diagnosed with deep venous thrombosis (DVT) between 1975 and 1980.
• Observed cases at the Surgical Department of Medizinische Akademie Magdeburg.
• Investigated potential causes for DVT in a female patient cohort.

Purpose:

• To identify potential risk factors associated with the occurrence of deep venous thrombosis in women.
• To evaluate the association between oral contraceptive use and the incidence of DVT.
• To determine if oral contraception should be considered a risk factor for venous thromboembolism.

Summary:

• Out of 48 women with DVT, 22 had no identifiable cause.
• A significant subset of 16 women had been using oral contraceptives for extended periods.
• While direct causality is not proven, oral contraceptive use emerged as a notable risk factor.

Impact:

• Highlights oral contraceptives as a potential risk factor for deep venous thrombosis.
• Suggests the need for further research into the mechanisms linking oral contraceptives and thrombosis.
• Informs clinical consideration of DVT risk in women using oral contraceptives.