Bilateral influences from the motor cortex on lumbar ventral horn interneurons

Microelectrode recordings were made of discharges of ventral horn interneurons (VHIN) in segments L6-7 of the spinal cord during bilateral stimulation of the motor cortex in cats. The overwhelming majority of VHIN was shown to be activated by influences from the contralateral cortex, and about half of them also by ipsilateral influences. Clear correlation was established between convergence of afferent and cortical influences: Neurons with inputs from ipsilateral afferents only were activated, irrespective of their other characteristics, by descending influences from the contralateral cortex only, whereas bilateral cortical influences converged on cells with bilateral afferent connections. It is suggested that VHIN with bilateral segmental and supraspinal connections are important integrative elements in the mechanism of bilateral coordination of motor responses of different degrees of complexity.