Hyperbaric oxygen and corneal incision healing

Corneal incision healing in the presence of daily or twice daily exposures to hyperbaric oxygen was compared in dogs to the natural course of such healing. Exposures lasted for 90 min and consisted of 60% oxygen administered at 60 fsw, an oxygen exposure of 2 ATA. Twenty corneas received such exposure, and 20 corneas were allowed to heal under natural conditions. Eyes were enucleated between 5 and 56 days after incision. The corneas were studied by gross observation and light microscopy. Uncomplicated and essentially comparable healing of the incisions occurred. There was a suggestion that superficial central clearing of the incision opacity occurred more quickly in the hyperbaric oxygen series.