Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Siderosis from a retained intraocular stone

S S Schocket, V Lakhanpal, S D Varma

    Retina (Philadelphia, Pa.)
    |January 1, 1981
    PubMed
    Summary

    A penetrating intraocular stone caused retinal detachment and siderosis. Despite surgical interventions and iron deposit clearing, progressive visual field loss occurred, highlighting long-term ocular risks.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Oxidative stress in lens in vivo: inhibitory effect of caffeine. A preliminary report.

    Molecular vision·2010
    Same author

    Intraocular penetration of pyruvate following its topical administration in mice.

    Molecular and cellular biochemistry·2009
    Same author

    Electron impact mass spectroscopic studies on mouse retinal fatty acids: effect of diabetes.

    Ophthalmic research·2009
    Same author

    Possibility of topical antioxidant treatment of cataracts: corneal penetration of pyruvate in humans.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2008
    Same author

    Oxidative damage to lens in culture: reversibility by pyruvate and ethyl pyruvate.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2005
    Same author

    Attenuation and delay of diabetic cataracts by antioxidants: effectiveness of pyruvate after onset of cataract.

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·2005

    Area of Science:

    • Ophthalmology
    • Retinal Diseases
    • Ocular Trauma

    Background:

    • Penetrating ocular trauma can lead to severe complications.
    • Intraocular foreign bodies, especially metallic ones, pose risks of infection and toxicity.
    • Early repair of retinal detachment is crucial for vision preservation.

    Observation:

    • A patient presented with siderosis bulbi 18 months after a penetrating intraocular stone injury and successful retinal detachment repair.
    • Serial neurosensory testing revealed progressive abnormalities, primarily in the electro-oculogram (EOG).
    • Fluorescein angiography showed retinal siderotic deposits and later pigment epithelial defects and cystoid macular edema.

    Findings:

    • Siderosis bulbi developed secondary to an intraocular stone, causing progressive visual field loss despite initial surgical management.
    • Electro-oculogram (EOG) demonstrated the most significant functional decline, while electroretinogram (ERG) and dark adaptation stabilized after initial impact.
    • Surgical removal of the foreign body via eye-wall resection led to vision recovery to 20/30, but visual fields remained constricted.

    Implications:

    • Intraocular metallic foreign bodies can cause delayed toxicity (siderosis) affecting retinal function.
    • Long-term monitoring with serial visual function tests is essential in patients with intraocular foreign bodies.
    • Ocular wall resection may be necessary for foreign body removal, with potential for partial visual field recovery.

    Related Experiment Videos