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Updated: Jun 23, 2026

Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery
Published on: December 23, 2014
Renovascular hypertension: treatment by percutaneous transluminal dilatation
Insights
Percutaneous transluminal dilatation effectively treated renovascular hypertension in most patients. This minimally invasive procedure improved or cured hypertension, with sustained vessel patency in the majority after six months.
Area of Science:
- Cardiology
- Nephrology
- Interventional Radiology
Background:
- Renovascular hypertension significantly impacts patient health.
- Surgical and medical treatments have limitations.
- Percutaneous transluminal dilatation offers a minimally invasive alternative.
Purpose of the Study:
- To evaluate the efficacy and safety of percutaneous transluminal dilatation for unilateral renovascular hypertension.
- To assess long-term outcomes including blood pressure control and renal artery patency.
Main Methods:
- Eight patients with unilateral renovascular hypertension underwent percutaneous transluminal dilatation.
- Stenoses were attributed to atherosclerosis or fibromuscular hyperplasia.
- Follow-up included clinical assessment and renal angiography at 6 months.
Main Results:
- Seven of eight patients experienced hypertension improvement or cure.
- Mean pressure gradient across stenoses decreased significantly post-procedure.
- Renal angiography showed vessel patency in five of six patients at 6 months.
Conclusions:
- Percutaneous transluminal dilatation is a valuable treatment for renovascular hypertension.
- The procedure demonstrates favorable outcomes and acceptable safety profile.
- Further research can explore its role in diverse patient populations.
Abstract:
Eight patients with unilateral renovascular hypertension underwent percutaneous transluminal dilatation. In seven, renal-artery stenoses were caused by atherosclerotic lesions and in one, by fibromuscular hyperplasia. After a 6-month follow-up period, three patients were cured of hypertension anf four showed improvement. Only one patient failed to respond: Failure was caused by an occluded left renal artery 3 months after the procedure. Renal angiographic studies were repeated in six patients after 6 months of follow-up and showed patent vessels in five and reoccurrence of a slight renal-artery stenosis in one. In one patient angiographic control studies done after 3 months showed an occluded renal artery. In five patients mean pressure gradient across the renal-artery stenoses was 89 +/- 22.8 mm Hg before percutaneous transluminal dilatation and 16.4 +/- 18.5 mm Hg after being controlled for 6 months. Our results indicate that percutaneous transluminal dilatation may be valuable in the treatment of renovascular hypertension.
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