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Symptomatic cerebral histoplasmoma. Case report

Journal of Neurosurgery
|February 1, 1980
PubMed

Insights

A rare brain tumor called histoplasmoma caused seizures in a patient with a history of lung surgery. This finding highlights the importance of considering histoplasmoma in the diagnosis of ring-shaped brain lesions, especially in those with prior pulmonary disease.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • A 53-year-old male with a history of thoracotomy presented with new-onset seizures.
  • Cerebral imaging is crucial for diagnosing neurological conditions.

Observation:

  • Computerized tomography (CT) scan with contrast revealed a peripheral ring-enhancing lesion in the right parietal lobe.
  • The lesion's location and appearance suggested a neoplastic or infectious etiology.

Findings:

  • Surgical resection and pathological examination identified the lesion as a histoplasmoma.
  • Histoplasmoma, a fungal granuloma caused by Histoplasma capsulatum, is an uncommon cause of intracranial lesions.

Implications:

  • This case underscores the importance of including histoplasmoma in the differential diagnosis of ring-enhancing brain lesions.
  • Patients with a history of pulmonary disease, particularly endemic fungal infections, should be evaluated for intracranial histoplasmoma when presenting with neurological symptoms.

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