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Symptomatic cerebral histoplasmoma. Case report

S S Schochet, M Sarwar, P J Kelly

    Journal of Neurosurgery
    |February 1, 1980
    PubMed
    Summary
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    A rare brain tumor called histoplasmoma caused seizures in a patient with a history of lung surgery. This finding highlights the importance of considering histoplasmoma in the diagnosis of ring-shaped brain lesions, especially in those with prior pulmonary disease.

    Area of Science:

    • Neurology
    • Infectious Diseases
    • Radiology

    Background:

    • A 53-year-old male with a history of thoracotomy presented with new-onset seizures.
    • Cerebral imaging is crucial for diagnosing neurological conditions.

    Observation:

    • Computerized tomography (CT) scan with contrast revealed a peripheral ring-enhancing lesion in the right parietal lobe.
    • The lesion's location and appearance suggested a neoplastic or infectious etiology.

    Findings:

    • Surgical resection and pathological examination identified the lesion as a histoplasmoma.
    • Histoplasmoma, a fungal granuloma caused by Histoplasma capsulatum, is an uncommon cause of intracranial lesions.

    Implications:

    • This case underscores the importance of including histoplasmoma in the differential diagnosis of ring-enhancing brain lesions.

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  • Patients with a history of pulmonary disease, particularly endemic fungal infections, should be evaluated for intracranial histoplasmoma when presenting with neurological symptoms.