Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A new ultrasound tissue-equivalent material

M M Burlew, E L Madsen, J A Zagzebski

    Radiology
    |February 1, 1980
    PubMed
    Summary

    A new agar-based tissue equivalent (TE) material offers improved stability and tunable sound speeds. This material overcomes limitations of traditional gelatin-based TE, enabling consistent production of materials with specific acoustic properties for various applications.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Contrasts between subsurface microbial communities and their metabolic adaptation to polycyclic aromatic hydrocarbons at a forested and an urban coal-tar disposal site.

    Microbial ecology·2013
    Same author

    EHPC 2010: sharing knowledge on environmental health for risk mitigation.

    Ecotoxicology (London, England)·2011
    Same author

    Investigating the biodegradability of perfluorooctanoic acid.

    Chemosphere·2010
    Same author

    Instrument for determining the complex shear modulus of soft-tissue-like materials from 10 to 300 Hz.

    Physics in medicine and biology·2008
    Same author

    Ultrasound frame rate requirements for cardiac elastography: experimental and in vivo results.

    Ultrasonics·2008
    Same author

    Acoustic backscatter and effective scatterer size estimates using a 2D CMUT transducer.

    Physics in medicine and biology·2008

    Area of Science:

    • Materials Science
    • Biomedical Engineering
    • Acoustics

    Background:

    • Traditional animal-hide gelatin and graphite powder tissue equivalent (TE) materials have limitations.
    • These limitations include inconsistent production of desired sound speeds (<1,570 m/s) and thermal instability (damage above 32.5°C).

    Purpose of the Study:

    • To develop a stable and consistently manufacturable tissue equivalent material.
    • To achieve a specific speed of sound (1,540 m/s) crucial for certain applications.

    Main Methods:

    • Investigated agar, a polysaccharide gel, as a substitute for gelatin.
    • Characterized the speed of sound and melting point of agar-based materials.
    • Assessed the thermal stability of the new material.

    Main Results:

    • Agar-based TE material exhibits a high melting point (78°C), indicating enhanced thermal stability.
    • Achieved tunable speeds of sound ranging from 1,498 m/s to over 1,600 m/s at 22°C.
    • Successfully manufactured agar-based TE material with a speed of sound of 1,540 m/s.

    Conclusions:

    • Agar-based tissue equivalent material is environmentally stable and overcomes the limitations of gelatin-based materials.
    • This new material allows for consistent manufacturing to achieve specific acoustic properties, particularly the target speed of sound (1,540 m/s).
    • The findings support the use of agar as a superior alternative for tissue equivalent material development.

    Related Experiment Videos